Urolithin A 8-Methyl Ether） 35233-17-1） video
Urolithin A 8-Methyl Ether （35233-17-1）speċifikazzjonijiet
| Isem tal-prodott | Urolithin A 8-Methyl Ether trab |
| Isem tal-kimika | 3-hydroxy-8-methoxy-6H-benzo [c] chromen-6-one;
3-hydroxy-8-methoxybenzo [c] chromen-6-one; 35233-17-1; MLS001049096; SMR000386929; ChemDiv3_002724; Urolithin A 8-Methyl Ether; |
| Numru CAS | 35233-17-1 |
| InChIKey | IGJLBTGXYKPECW-UHFFFAOYSA-N |
| Molekulari Formula | C14H10O4 |
| Molekulari W8 | 242.23 |
| Massa Monoisotopika | 242.057909 g / mol |
| Punt tat-tidwib | 242 ° C (Solv: aċidu aċetiku (64-19-7)) |
| Punt ta 'togħlija | 479.9 ± 38.0 ° C (Prevedut) |
| Deżità | 1.375 ± 0.06 g / cm3 (Prevedut) |
| Half-Life bijoloġiku | N / A |
| kulur | Beige ċar għal solidu oranġjo skur ħafna |
| Solubilità | Aċetun (Ftit, Sonikat) DMSO (Ftit, Sonikat), Metanol (Ftit) |
| Storage Timperature | Hygroscopic, -20 ° C Freezer, Taħt atmosfera inerta |
| AApplikazzjoni | Urolithin A 8-Methyl Ether huwa sustanza intermedja fis-sintesi ta 'Urolithin A (U847000), metabolit ewlieni ta' Ellagitannin u juri proprjetajiet anti-infjammatorji u anti-ossidanti. |
Referenza
[1] Espín, Juan Carlos; Larrosa, Mar; García-Conesa, María Teresa; Tomás-Barberán, Francisco (2013). "Sinifikat Bijoloġiku ta 'Urolithins, il-Metaboli derivati mill-Aċidu Ellagiku Mikrobjali tal-Gut: L-Evidenza S'issa". Mediċina Kumplimentari u Alternattiva Ibbażata fuq l-Evidenza. 2013: 270418. doi: 1155/2013/270418. ISSN1741-427X. PMC 3679724. PMID 23781257.
[2] Ryu, Dongryeol; Mouchiroud, Laurent; Andreux, Pénélope A; Katsyuba, Elena; Moullan, Norman; Nicolet-dit-Félix, Amandine A; Williams, Evan G; Jha, Pooja; Sasso, Giuseppe Lo (2016). "L-Urolitina A tinduċi mitofaġija u ttawwal il-ħajja f'C. Elegans u żżid il-funzjoni tal-muskoli f'annimali gerriema". Mediċina tan-Natura. 22 (8): 879-888. doi: 1038 / nm.4132. PMID 27400265.
[3] Ishimoto, Hidekazu; Shibata, Mari; Myojin, Yuki; Ito, Hideyuki; Sugimoto, Yukio; Tai, Akihiro; Hatano, Tsutomu (2011). "Proprjetajiet anti-infjammatorji u anti-ossidanti in vivo tal-metabolit ellagitannin urolithin A" (PDF). Ittri tal-Kimika Bijoorganika u Mediċinali. 21 (19): 5901–5904. doi: 1016 / j.bmcl.2011.07.086. PMID 21843938.
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